Neil Patrick Harris could have been one of the original cast members of the hit FX anthology series "American Horror Story" if only he did not turn down a previous offer to appear on the show's first installment subtitled "Murder House."

The 41-year-old actor stopped by Entertainment Weekly Radio on Sirius XM Thursday, Oct. 16 - a day after the news broke that he would be hosting the Oscars - and revealed that showrunner Ryan Murphy asked him and his husband David Burtka to play a couple in the show's first season.

But the two had just portrayed a dysfunctional "couple" in the 2011 3D stoner comedy film "A Very Harold and Kumar 3D Christmas," and the "Gone Girl" star did not want to play the same roles twice, so they refused to play the roles, which eventually went to Zachary Quinto and Teddy Sears.

"Right after that [Christmas film], we were asked to be in season one of this great new show called 'American Horror Story,' revealed the five-time Primetime Emmy winner to  EW editor Matt Bean. "And the idea was that we would be a gay couple, that, as it turns out, were murdered in this house and then our ghosts are around for the thing."

"It seemed cool," he said of the project. "Loved Ryan [Murphy, loved the idea of a horror anthology show. Knew nothing about it, but we had just played ourselves as a couple, not getting along, and I thought, it just seems weird to do that twice, like as individual actors, to play a couple that hates each other twice. It just felt weird."

"So I said no, that we shouldn't do it. And David wanted to. I said, 'I just don't want us to be known as a couple that don't like each other,'" he explained. "And then wouldn't you know, 'American Horror Story' is a big, gigantic success and super awesome."

But Harris is now set to appear on the current season of "American Horror Story" called "Freak Show."

Earlier this month before the fourth installment premiere of the Primetime Emmy-winning show, Murphy told a group of reporters that Harris is "game" to make an appearance on the horror series.  

"He had very specific ideas of what he wanted to do, and I had very specific ideas, so we're melding them, Murphy said, as quoted by E! News. "He's awesome... I would love to see him and Jessica Lange go at it in some intriguing way. Because of his schedule, something we're thinking about, maybe one episode and then another one later on."

In an interview with Vulture last month, Harris opened up about why he loves the anthology series.

"I just watched the end of 'American Horror Story: Coven,' and not only is the content amazing, the conceit of the show, but the people that they have are extraordinary!" Harris said. "Jessica Lange is so good! All of them, they're all uniformly talented. So to get to play in that sandbox would be a great bucket-list moment."